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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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SPI-112 is a small-molecule, selective and competitive inhibitor of SHP2 (PTPN11) used for biochemical and cellular research. It inhibits SHP2 and related protein tyrosine phosphatases and is supplied as a solid with guidance for storage and preparation of solution stocks.
Selective and competitive inhibition of SHP2 for pathway studies.
Reported IC50 values support biochemical assay characterization.
High purity solid suitable for preparation of DMSO stocks.
Available in small milligram quantities and as a prepared solution for convenience.
Storage recommendations provided to preserve compound stability.
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hsa-miR-122-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Rapastinel trifluoroacetate is a peptide-based NMDA receptor modulator used in preclinical research to investigate antidepressant-related mechanisms and receptor pharmacology. It is supplied as a white to off-white solid with high purity and defined storage recommendations.
High purity (98.0%) suitable for research applications.
Peptide NMDA receptor modulator with glycine-site partial agonist activity.
White to off-white solid, convenient for formulation and dosing.
Available in small milligram quantities for in vitro and in vivo studies.
Recommended storage: sealed, away from moisture; in solvent -80°C (up to 6 months).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
UC-112 is a survivin and XIAP modulator that demonstrates anticancer activity. It works by selectively downregulating and degrading survivin through the ubiquitin-mediated proteasomal degradation pathway. It also reduces XIAP levels in in vivo tumor models, activates caspase-3/7 and caspase-9, and induces apoptosis in cancer cells. This product is for research use only and not for patient use.
Selectively downregulates and degrades survivin
Reduces XIAP levels in in vivo tumor models
Activates caspase-3/7 and caspase-9, inducing cancer cell apoptosis
Inhibits proliferation of A375, M14, PC-3, and DU145 cancer cells
Inhibits human melanoma tumor growth in nude mice
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More